[Bioinformatics] Monday's Bioinformatics Seminar: Terry Speed, Ph.D.
Bioinformatics IDP-Seminar Series
bioinformatics at lists.ucla.edu
Wed Apr 29 08:25:16 PDT 2009
MONDAY, May 4, 2009
Terry Speed, Ph.D.
Department of Statistics; Interdepartmental Group in Biostatistics, and the Graduate Group in Computational and Genomic Biology, UC Berkeley
"Statistical Challenges with
Next-Generation Sequence Data"
Recent improvements in the efficiency, quality, and cost of genome-wide sequencing are prompting biologists to abandon microarrays in favor of next-generation sequencers, e.g., Applied Biosystems' SOLiD, Helicos BioSciences' HeliScope, Illumina's Solexa, and Roche's 454 Life Sciences sequencing systems, and more. These high-throughput sequencing technologies have already been applied to studying genome-wide transcription levels (mRNA-Seq), transcription factor binding sites (ChIP-Seq), chromatin structure, DNA copy number, and DNA methylation status and other topics. This talk, which draws heavily on work of Sandrine Dudoit and her students, and my student Oleg Mayba, touches on some of these areas, with the major focus being on ChIP-Seq. http://www.stat.berkeley.edu/~terry/
Host: Matteo Pellegrini
*Refreshments will be served after the seminar at 5:00 pm*
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